Basic Information
VIS ID
TVIS44022907
Fusion event
HTLV-1-chr8 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.13
Reference genome
GRCh37/hg19
Start
79981563/79069328 (Hg38)
End
79981563/79069328 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-124-1/Upstream/2102478; hsa-mir-10400/Downstream/262860;
Nearest TSS
ENST00000518652/Upstream/231799; ENST00000519983/Downstream/228389;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/264160, chr8-CpG: 38/Downstream/542412
Nearby gene
IL7(-263805) ;
Upstream sequence
ACACTCTAGAGAAATCAACCAAAAGATGATAATTCTCATGATAAAATAATTTCCAGAAGACAAATGATATAAATAAAGAATTCTAAATAAAAATGGGTAC
Downstream sequence
TTCTTCATTTTTGCTTTGTGGGGAAGACATCAATGCTGTAGCAATCACACTTTTGAAATACCATTCTAAACCTAGCTTTGGTAAGCAATCACCTGCTGTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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