Basic Information
VIS ID
TVIS44022916
Fusion event
HTLV-1-LOC105375937 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
86445409/85533180 (Hg38)
End
86445409/85533180 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375937
Nearest miRNA
hsa-mir-12123/Upstream/5291707; hsa-mir-10400/Downstream/5672305;
Nearest TSS
ENST00000518652/Upstream/9281; ENST00000517368/Downstream/306525;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/68695, chr8-CpG: 127/Downstream/109267
Nearby gene
CA2(+51688) ;
Upstream sequence
GACTCAGTAACTTTGAAAATAATCTCTGTATTGACATGGTTCAGGTAACGGACCCTCAAAATGGAAGTGTTAAGTTGGTTCTATCACAGAGATTAATTAT
Downstream sequence
TCTTTGGGAAACAAGTGAAAATTAACAAATTGATTTCATGTGGTATCCAAACTTGTGCACAGCCCTTGCAATAATCATTGAAAGTTATTTAGCACAGAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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