VISDB Viral Integration Site DataBase

VIS ID

TVIS44022924

Fusion event

HTLV-1-C8orf37 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr8

Cytoband

q22.1

Reference genome

Start

End

96262646/95250418 (Hg38)

Orient

+

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-7156-3p ; hsa-mir-6516-3p ; hsa-mir-1206 ; hsa-mir-1255b-5p ; hsa-mir-1255a ; hsa-mir-8084 ; hsa-mir-340-5p ; hsa-mir-503-3p ; hsa-mir-6861-5p ; hsa-mir-186-3p ; hsa-mir-885-5p ; hsa-mir-382-3p ; hsa-mir-3159 ; hsa-mir-541-5p ; hsa-mir-551b-5p ; hsa-mir-3149 ; hsa-mir-374a-3p ; hsa-mir-411-5p ; hsa-mir-4775 ; hsa-mir-6832-5p ; hsa-mir-4694-5p ; hsa-mir-1273f ; hsa-mir-4735-5p ; hsa-mir-590-3p ; hsa-mir-670-3p ; hsa-mir-4752 ; hsa-mir-6833-5p ; hsa-mir-644a ; hsa-mir-3190-3p ; hsa-mir-8053 ; hsa-mir-6077 ; hsa-mir-6717-5p ; hsa-mir-7-5p ; hsa-mir-145-3p ; hsa-mir-4289 ; hsa-mir-4302 ; hsa-mir-3941 ; hsa-mir-759 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-3117-5p ; hsa-mir-372-5p ; hsa-mir-371a-5p ; hsa-mir-616-5p ; hsa-mir-373-5p ; hsa-mir-371b-5p ; hsa-mir-3613-3p ; hsa-mir-4282 ; hsa-mir-4666b ; hsa-mir-3978 ; hsa-mir-150-5p ; hsa-mir-216b-5p

Nearest miRNA

hsa-mir-12123/Upstream/177422; hsa-mir-10400/Downstream/3143227;

Nearest TSS

Nearest CpG islands

None/Target, chr8-CpG: 109/Upstream/115917, chr8-CpG: 74/Downstream/18198

Upstream sequence

AATCCTCTAGTTGTCACTGTTTTATCTAAAAGTACATATATTTTTTAAACCAGGCTGCCACAGATCTAGGGTAAACCaactggtgttcttgataactctg

Downstream sequence

agatgctgcaagttcctcaagtaccgactaggttatccatagtttactttatgcctgtgttcaccactgccttgatgttacatgcattttattatcctat