Basic Information
VIS ID
TVIS44022926
Fusion event
HTLV-1-C8orf37-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
96321987/95309759 (Hg38)
End
96321987/95309759 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA8B
Target gene
C8orf37-AS1
Nearest miRNA
hsa-mir-12123/Upstream/236763; hsa-mir-10400/Downstream/3083886;
Nearest TSS
ENST00000518652/Upstream/40558; ENST00000519366/Downstream/122878;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/40240, chr8-CpG: 118/Downstream/834776
Upstream sequence
TATGAACAGAGAGGAGAGTCACTGCCTTTTCTTAGGATAGTGAAAAATTTCAAGTTAATTTTTAAAGGTGTTCTTTGCGGAGATTTTAAACACCTTAAGG
Downstream sequence
GTAGGGACCAGACCCTCTTCCTTTTATCTTGTCCTTGCCTCTCATTTTCTCAGGTGTGGTCTTTTAGGCAGAATGAGCACTATTAGTGTATTTGACAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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