Basic Information
VIS ID
TVIS44022934
Fusion event
HTLV-1-GRIN3A integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
104488746/101726464 (Hg38)
End
104488746/101726464 (Hg38)
Orient
+
Location type
Intronic
Target gene
GRIN3A
miRNAs that regulate target gene
hsa-mir-542-5p
Nearest miRNA
hsa-let-7a-1/Upstream/3497247; hsa-mir-12126/Downstream/4874464;
Nearest TSS
ENST00000422679/Upstream/112942; ENST00000374801/Downstream/12116;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/192514, chr9-CpG: 115/Downstream/11103
Upstream sequence
GTGAGAAACTGAGAGAAGAGCCATTGGGCCCCAGAGCAAGGGAAAAAGAGAGGTGCTACCCAAACACCTTCTGGTGGTACAGCTCAGCTATACTTCATGC
Downstream sequence
ATTTCTATTTCATGTCATTTTCCTGTAAGATTTCAGCACAAATTCCCTGCTTTTGAGCTTCATGGTGGGAGTTTCTCTTCCTTTGCAACAGAACATCCTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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