VISDB Viral Integration Site DataBase

VIS ID

TVIS44022943

Fusion event

HTLV-1-PALM2-AKAP2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

q31.3

Reference genome

Start

End

112770150/110007870 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-98-5p ; hsa-mir-511-3p ; hsa-mir-190a-3p ; hsa-mir-5011-5p ; hsa-mir-6867-5p ; hsa-mir-3613-3p ; hsa-mir-4491 ; hsa-mir-4657 ; hsa-mir-432-5p ; hsa-mir-574-5p ; hsa-mir-1277-5p ; hsa-mir-6083 ; hsa-mir-223-5p ; hsa-mir-299-3p ; hsa-mir-6836-3p ; hsa-mir-106a-3p ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-185-3p ; hsa-mir-4283 ; hsa-mir-4489 ; hsa-mir-4741 ; hsa-mir-4675 ; hsa-mir-7974 ; hsa-mir-6882-3p ; hsa-mir-6829-3p ; hsa-mir-6791-3p ; hsa-mir-6778-3p ; hsa-mir-4800-5p ; hsa-mir-3138 ; hsa-mir-6730-3p ; hsa-mir-651-5p ; hsa-mir-3941 ; hsa-mir-3177-5p ; hsa-mir-3159 ; hsa-mir-603 ; hsa-mir-8485 ; hsa-mir-629-3p ; hsa-mir-6873-3p ; hsa-mir-4684-5p ; hsa-mir-4279 ; hsa-mir-1200 ; hsa-mir-378a-5p ; hsa-mir-211-5p ; hsa-mir-204-5p ; hsa-mir-642a-5p ; hsa-mir-4724-3p ; hsa-mir-6817-3p ; hsa-mir-7110-3p ; hsa-mir-4685-3p ; hsa-mir-4287 ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6832-3p ; hsa-mir-4667-3p ; hsa-mir-1470 ; hsa-mir-145-3p ; hsa-mir-130b-5p ; hsa-mir-6507-3p

Nearest miRNA

hsa-let-7a-1/Upstream/496325; hsa-mir-12126/Downstream/1263286;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/227483, chr9-CpG: 23/Downstream/40777

Upstream sequence

tttaacatgtgcatgggagccttcagaaggaatacccaaagatagaggtgaaattgcccatttttgtacttagtttcaacaaagtttggacagccatgta

Downstream sequence

gatctaaaaaggatataatctaatgttaatagacagtgaggaaacccagcaaggcctgtctgtctagattcttcttcagcatgcatcctctaagcatgca