Basic Information
VIS ID
TVIS44022980
Fusion event
HTLV-1-ANAPC2 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
140081929/137187477 (Hg38)
End
140081929/137187477 (Hg38)
Orient
+
Location type
Intronic
Target gene
ANAPC2
Nearest miRNA
hsa-let-7a-1/Upstream/18207; hsa-mir-602/Downstream/262549;
Nearest TSS
ENST00000422679/Upstream/968; ENST00000463511/Downstream/1060;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/2165, chr9-CpG: 145/Downstream/536
Upstream sequence
TATCAGGACGGCTCACCAGCTTTCTGCTGAGGCCAGCTGGACCCAGGGGAGCAGCGGGGAACCAGAAGGAGCAAGGGCATGGCCATCGGGACAGACTACT
Downstream sequence
CACAAGACCTGGCTGAGCTGATGGAACTGCTCCAGAGCCTGGCGACACCAGCACTGTTGCTTGTCACTGCTGCACCCTGCACACAGCGGGCTCTGCAGGA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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