Basic Information
VIS ID
TVIS44022986
Fusion event
HTLV-1-LOC105375951 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p24.3
Reference genome
GRCh37/hg19
Start
1817427/1817427 (Hg38)
End
1817427/1817427 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105375951
Nearest miRNA
hsa-mir-1302-9/Upstream/1787146; hsa-let-7a-1/Downstream/3032870;
Nearest TSS
ENST00000422679/Upstream/762803; ENST00000637134/Downstream/162863;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/765187, chr9-CpG: 266/Downstream/197404
Nearby gene
SMARCA2(+197792) ;
Upstream sequence
cccaaagtgctgggattacaagcatgagccaccacgcccagccTCTTCTTACTTTTAATAGTGCCTAGAGTAGGAAGCTCAGTTCCTTATAATTATTTAT
Downstream sequence
AAAGgagatcttagattgagaatgaaagctatgtttatgctgggatccaggtgtggctgaacatgtcttggagagactgcttgggtagtccgttagaaaa
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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