Basic Information
VIS ID
TVIS44022994
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
22547217/22547218 (Hg38)
End
22547217/22547218 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA9C
Nearest miRNA
hsa-mir-101-2/Upstream/1035033; hsa-let-7a-1/Downstream/6316408;
Nearest TSS
ENST00000422679/Upstream/100377; ENST00000433645/Downstream/98982;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/99522, chr9-CpG: 156/Downstream/1273475
Nearby gene
DMRTA1(+94745) ;
Upstream sequence
CTGCTGTTTGAATTAATGTATGGATTAAGTTGATGTAACAAAGAGTCACAAAAATAAATGTTAACATTTCTTTTGTCTTCAATTTCCTAAAATTATTTCT
Downstream sequence
CAGTTCATTTGAAAACTACAATGATAATATGTAAATTATGTTTGGGCTTCATAAAAATCTTTGTATTTCCTAAGCTTTAAATTTCCACCAAGAAACCCTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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