VISDB Viral Integration Site DataBase

VIS ID

TVIS44023012

Fusion event

HTLV-1-RECK integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr9

Cytoband

p13.3

Reference genome

Start

End

36119472/36119475 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-373-3p ; hsa-mir-15b-5p ; hsa-mir-21-5p ; hsa-mir-222-3p ; hsa-mir-15a-5p ; hsa-mir-182-5p ; hsa-mir-335-5p ; hsa-mir-124-3p ; hsa-mir-103a-3p ; hsa-mir-16-5p ; hsa-mir-25-3p ; hsa-mir-374b-5p ; hsa-mir-221-3p ; hsa-mir-195-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-562 ; hsa-mir-4524a-5p ; hsa-mir-4524b-5p ; hsa-mir-6838-5p ; hsa-mir-96-5p ; hsa-mir-92b-3p ; hsa-mir-7847-3p ; hsa-mir-1294 ; hsa-mir-6880-5p ; hsa-mir-6894-5p ; hsa-mir-7154-3p ; hsa-mir-765 ; hsa-mir-766-5p ; hsa-mir-5192 ; hsa-mir-4722-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-4693-3p ; hsa-mir-4768-3p ; hsa-mir-3922-5p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-5586-3p ; hsa-mir-3714 ; hsa-mir-1271-5p ; hsa-mir-29b-2-5p ; hsa-mir-190a-3p ; hsa-mir-299-5p ; hsa-mir-410-3p ; hsa-mir-646 ; hsa-mir-618 ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-503-5p ; hsa-mir-135b-5p ; hsa-mir-15b-3p ; hsa-mir-409-3p ; hsa-mir-590-5p ; hsa-mir-183-5p

Nearest miRNA

hsa-mir-101-2/Upstream/386480; hsa-let-7a-1/Downstream/704064;

Nearest TSS

Nearest CpG islands

None/Target, chr9-CpG: 64/Upstream/81908, chr9-CpG: 114/Downstream/16716

Nearest cancer related gene

RECK(TSG, No orient, 0)

Upstream sequence

GAAGATAGTTGTTGTCTTAGATTGGCCTTAACATCTAATTTAATTGTTTTAGTTGCATATAATCAGAAAAGTTTTGTTTCATACAGACTGTTTTTAGCAA

Downstream sequence

TAACAGTTTTTTAAAACAGCTTACCTTACAATCTCACACTCTTAGTCAAACAGAAGTAGCAGAAGAGACTTTATTCCAAGTCTGCACAGAACAGGTTAAT