Basic Information
VIS ID
TVIS44023042
Fusion event
HTLV-1-chr9 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q21.33
Reference genome
GRCh37/hg19
Start
89960667/87345752 (Hg38)
End
89960667/87345752 (Hg38)
Orient
-
Location type
Intergenic
Nearest miRNA
hsa-mir-101-2/Upstream/3375895; hsa-let-7a-1/Downstream/1400084;
Nearest TSS
ENST00000422679/Upstream/197108; ENST00000470267/Downstream/151476;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/196900, chr9-CpG: 145/Downstream/151847
Nearby gene
DAPK1(+151476) ;
Nearest cancer related gene
DAPK1(TSG, +151476) ;
Upstream sequence
CCAAAATAACAGTCATTTTAGACCAATCAGGATTTTCTTTGCACAGCCTATCCTAGCCTGAGGAGAGCCTCCAAGAAGGGCCCTACATCCTATCAGTCAC
Downstream sequence
CAAGGTGACTCGCCGCCATCTTGAAGGTTCTCCAACATGGAGTCTTGTGCCCCAGGTGTGAGTGGACAAGGGTCACCCTGCTGACCTTGTTGCCACAGCA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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