Basic Information
VIS ID
TVIS44023055
Fusion event
HTLV-1-GALNT12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q22.33
Reference genome
GRCh37/hg19
Start
101578297/98816015 (Hg38)
End
101578297/98816015 (Hg38)
Orient
+
Location type
Intronic
Target gene
GALNT12
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-215-5p ; hsa-mir-192-5p
Nearest miRNA
hsa-let-7a-1/Upstream/586798; hsa-mir-12126/Downstream/7784913;
Nearest TSS
ENST00000422679/Upstream/8012; ENST00000615204/Downstream/21060;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/7948, chr9-CpG: 75/Downstream/127610
Upstream sequence
gaccattctcctttatcattaaatattctctaaaaaatgttattttGTTGTTTTACGTGGTGCCTCTCATGTAGTAAACACTCAACAAAGGGTACTGTTA
Downstream sequence
TTACCAGGTAAAGTACAAGGCGTGCTGAAAATACATGGCCATGATTTCCTCATGCAGCCATACTATACTATattttcttcttgttcgacattgaaattgt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate