Basic Information
VIS ID
TVIS44023065
Fusion event
HTLV-1-LOC105378464 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q25.1
Reference genome
GRCh37/hg19
Start
106380345/104620587 (Hg38)
End
106380345/104620587 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA10D ; FRA10A ; FRA10B
Target gene
LOC105378464
Nearest miRNA
hsa-mir-107/Upstream/352182; hsa-mir-202/Downstream/6277503;
Nearest TSS
ENST00000439456/Upstream/4485; ENST00000393176/Downstream/20514;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/281789, chr10-CpG: 281/Downstream/19222
Nearby gene
SORCS3(+20514) ;
Upstream sequence
GGATAAGAAACTCAGTGATTTAGATGAAAACTTTCCATGCAATTAACTTTCTCCAGACTAAAGCAGGTGCGGAAGGGAGCTACTGGGCCAGTCTGCTTAG
Downstream sequence
TAAATATCTATCCCCAGATGGAGAGCAATTCAATGGAAATAATTACACCAGGTCAATTAAGCAGAACTCAGATCTCCTCCTGTTAGCCCTTTTGAATTTT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate