Basic Information
VIS ID
TVIS44023084
Fusion event
HTLV-1-MIR5694 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q26.12
Reference genome
GRCh37/hg19
Start
122634434/120874922 (Hg38)
End
122634434/120874922 (Hg38)
Orient
-
Location type
ncRNA_intronic
Fragile sites / regions
FRA10D ; FRA10F ; FRA10A ; FRA10B
Target gene
MIR5694
Nearest miRNA
hsa-mir-107/Upstream/916330; hsa-mir-202/Downstream/1542043;
Nearest TSS
ENST00000439456/Upstream/6259; ENST00000605376/Downstream/4083;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/23382, chr10-CpG: 31/Downstream/74075
Upstream sequence
gttctgggatacatgtgcagaatgtgcaggtttgttacatagatatacatgtgccttggtggtttgctgcacctgtcaacccgtcatctaggttttaagc
Downstream sequence
cccacatgcattaggtatttctcctaatgctctccctccccttgcccctcaatccccgataggccccagtgtgtgatgttcctctcgctgtgtctatgtg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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