Basic Information
VIS ID
TVIS44023099
Fusion event
HTLV-1-PTER integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p13
Reference genome
GRCh37/hg19
Start
16485628/16443629 (Hg38)
End
16485628/16443629 (Hg38)
Orient
-
Location type
Intronic
Target gene
PTER
miRNAs that regulate target gene
hsa-mir-130b-3p ; hsa-mir-29c-5p
Nearest miRNA
hsa-mir-1265/Upstream/2006968; hsa-mir-107/Downstream/1401478;
Nearest TSS
ENST00000439456/Upstream/6645; ENST00000485788/Downstream/40706;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/6325, chr10-CpG: 195/Downstream/75976
Upstream sequence
GGAGAATCTCCTCAGTTCAGGAACTTCTTTTTAACTAACATTACTTGGAGGAGAGCTTAATGCTCGTGACTTTAAACATTTATGTAATTAGGTAAAAAGG
Downstream sequence
GAAGCAACATTATTAAATGACTTGGATAGAGTTCATCAAGCAGTTAAGAAAAAAATGTACATAATcaagcgtaccttgcagtctgaatgacaaacatcca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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