Basic Information
VIS ID
TVIS44023102
Fusion event
HTLV-1-NSUN6 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p12.31
Reference genome
GRCh37/hg19
Start
18879946/18591017 (Hg38)
End
18879946/18591017 (Hg38)
Orient
+
Location type
Intronic
Target gene
NSUN6
Nearest miRNA
hsa-mir-1265/Upstream/745824; hsa-mir-107/Downstream/1960953;
Nearest TSS
ENST00000439456/Upstream/39195; ENST00000377275/Downstream/60605;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/449726, chr10-CpG: 24/Downstream/60582
Upstream sequence
gacacaaaaaacccttcaaagaatgaattgaggagctggttttttgaaaagattaacaaaacagaccattagctagactaacacagaagaaaacaaagaa
Downstream sequence
gaatcaaacagacacaataaaaaatgataaaggggatgtcaccactgatcccaaagaaatacaaactgccatcagagaatactataaacccctccatgca
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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