Basic Information
VIS ID
TVIS44023123
Fusion event
HTLV-1-LOC105376500 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
p11.1
Reference genome
GRCh37/hg19
Start
38451548/38162620 (Hg38)
End
38451548/38162620 (Hg38)
Orient
+
Location type
Intronic
Target gene
LOC105376500
Nearest miRNA
hsa-mir-1265/Upstream/2521368; hsa-mir-107/Downstream/4834943;
Nearest TSS
ENST00000439456/Upstream/25283; ENST00000428915/Downstream/290561;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/67586, chr10-CpG: 41/Downstream/193564
Nearby gene
LOC100129055(+13051) ;
Upstream sequence
aaaatcttaataaatgaaaaatcagtaaataaaaaatgaatataaaataCCTAAACATAAATTTGTCCTAAAACTCTAGTTGAGGGTTTTAAACATATCA
Downstream sequence
AGAGTAACTGTTTTGAGTCACCTTAAAGCATTGCAATTTGTACAACCAAAAGGAAATATATCCTAAGGAAAAAATGAATTGCCAAACGAGGACCCTAAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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