Basic Information
VIS ID
TVIS44023124
Fusion event
HTLV-1-ZNF32-AS3 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q11.21
Reference genome
GRCh37/hg19
Start
44150704/43655256 (Hg38)
End
44150704/43655256 (Hg38)
Orient
+
Location type
ncRNA_intronic
Fragile sites / regions
FRA10G
Target gene
ZNF32-AS3
Nearest miRNA
hsa-mir-1265/Upstream/657575; hsa-mir-107/Downstream/1508758;
Nearest TSS
ENST00000439456/Upstream/6400; ENST00000418426/Downstream/10412;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/6006, chr10-CpG: 59/Downstream/12146
Upstream sequence
agctctgactttgtcctcagcttctggcaggtgatctatctccaagcccttggagtatagtgcttaataggattgtcttcatttgccagtggcctgggct
Downstream sequence
cacgctgggtagtctagatgtgatttacggtggggctgccccactgggtagtctcaggatgggacctggacactccaggtggtaacgacatgctatgggt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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