Basic Information
VIS ID
TVIS44023150
Fusion event
HTLV-1-CABCOCO1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
63473087/61713329 (Hg38)
End
63473087/61713329 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA10C
Target gene
CABCOCO1
Nearest miRNA
hsa-mir-1265/Upstream/4408770; hsa-mir-107/Downstream/1659628;
Nearest TSS
ENST00000439456/Upstream/27941; ENST00000644638/Downstream/107917;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/49982, chr10-CpG: 44/Downstream/189798
Upstream sequence
taagttggattcctaggtattttatcctctttgtagcaattgtgaatgggagttcactcatgatttggctctctgtttgtctgttattcgtgtataagaa
Downstream sequence
tgccttgtgattgatttttgcacattgattttgtatcctgagactttgctgaagttgctaatcaccttagggagattttgggctgaaacgatggggtttt
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate