Basic Information
VIS ID
TVIS44023160
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q22.1
Reference genome
GRCh37/hg19
Start
72053363/70293607 (Hg38)
End
72053363/70293607 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA10C
Nearest miRNA
hsa-mir-1265/Upstream/2890197; hsa-mir-107/Downstream/1497140;
Nearest TSS
ENST00000439456/Upstream/9931; ENST00000373218/Downstream/83172;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/9477, chr10-CpG: 108/Downstream/88197
Nearby gene
LRRC20(-5363) ;
Upstream sequence
AGGAAATATGACCCAAAATCTAGAAAAGAGACAAAGATGATAACTGCATTGTTCAACAGGCCTGCCTGTgagaatgtaccactgtaactttgttagttac
Downstream sequence
tattaattaaaggcacagactctgtgaggttacttgttaacttatggattcctgtccggcagaaaaaaataaccccaagttgactttatcagctggcagg
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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