VISDB Viral Integration Site DataBase

VIS ID

TVIS44023163

Fusion event

HTLV-1-UNC5B integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr10

Cytoband

q22.1

Reference genome

Start

End

73043997/71284240 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-124-3p ; hsa-mir-92b-3p ; hsa-mir-193b-3p ; hsa-mir-6895-3p ; hsa-mir-432-5p ; hsa-mir-218-5p ; hsa-mir-4646-5p ; hsa-mir-450a-2-3p ; hsa-mir-6803-5p ; hsa-mir-6751-5p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-7110-5p ; hsa-mir-92a-1-5p ; hsa-mir-6842-5p ; hsa-mir-6752-5p ; hsa-mir-6835-5p ; hsa-mir-6780b-5p ; hsa-mir-4271 ; hsa-mir-4725-3p ; hsa-mir-765 ; hsa-mir-6077 ; hsa-mir-4784 ; hsa-mir-3150b-3p ; hsa-mir-7155-5p ; hsa-mir-637 ; hsa-mir-4700-5p ; hsa-mir-8089 ; hsa-mir-4667-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-5582-5p ; hsa-mir-4262 ; hsa-mir-181d-5p ; hsa-mir-181c-5p ; hsa-mir-181b-5p ; hsa-mir-181a-5p ; hsa-mir-6768-5p ; hsa-mir-8485 ; hsa-mir-8073 ; hsa-mir-221-5p ; hsa-mir-483-3p ; hsa-mir-4279 ; hsa-mir-8064 ; hsa-mir-6845-3p ; hsa-mir-622 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-4435 ; hsa-mir-4666a-5p ; hsa-mir-3190-5p ; hsa-mir-6794-3p ; hsa-mir-1262 ; hsa-mir-1271-3p ; hsa-mir-214-5p ; hsa-mir-3689d ; hsa-mir-4266 ; hsa-mir-4651 ; hsa-mir-4695-5p ; hsa-mir-4701-3p ; hsa-mir-4779 ; hsa-mir-4781-5p ; hsa-mir-550a-3-5p ; hsa-mir-550a-5p ; hsa-mir-608 ; hsa-mir-6514-3p ; hsa-mir-6736-5p ; hsa-mir-6748-5p ; hsa-mir-6756-5p ; hsa-mir-6766-5p ; hsa-mir-6769a-5p ; hsa-mir-6769b-5p ; hsa-mir-6811-3p ; hsa-mir-6851-5p

Nearest miRNA

hsa-mir-1265/Upstream/3880830; hsa-mir-107/Downstream/506507;

Nearest TSS

Nearest CpG islands

None/Target, chr10-CpG: 68/Upstream/66223, chr10-CpG: 37/Downstream/92974

Nearest cancer related gene

UNC5B(TSG, No orient, 0)

Upstream sequence

tgctgggagagctgtcggggaggcgcagggtggagggggctttcctcgggaagtgaggctgatccgaaatctggcagggactgggaggccaccaggccca

Downstream sequence

gaggagacagaagattccaggcaggggactgatgtgcaagggccccgtggctgcagagccagggaacatgagggcctggaagacacccggtgaggctgca