Basic Information
VIS ID
TVIS44023173
Fusion event
HTLV-1-chr10 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr10
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
88170776/86411019 (Hg38)
End
88170776/86411019 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA10D
Nearest miRNA
hsa-mir-1265/Upstream/146231; hsa-mir-107/Downstream/1092862;
Nearest TSS
ENST00000439456/Upstream/44526; ENST00000428940/Downstream/33013;
Nearest CpG islands
None/Target, chr10-CpG: 68/Upstream/9159, chr10-CpG: 137/Downstream/109859
Nearby gene
WAPL(No orient, 24237)
Nearest cancer related gene
WAPL(OG, No orient, 24237)
Upstream sequence
TAAGTATCtgtctcagtcagctatagctgtgtaacaaagtacacccaaacttggttggtcaaaacagcatttgttactcatgattctgtggagtttggca
Downstream sequence
gagctcagtgggcatagcttatccttctccacatggtgtcctcgggtggttcaactagggctggaggATCCAACACACCTCCCTCCCTGTGTGGGCCTTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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