VISDB Viral Integration Site DataBase

VIS ID

TVIS44023200

Fusion event

HTLV-1-PAFAH1B2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q23.3

Reference genome

Start

End

117032014/117161298 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

FRA11G ; FRA11B

Target gene

miRNAs that regulate target gene

hsa-mir-16-5p ; hsa-mir-30a-5p ; hsa-mir-615-3p ; hsa-mir-15a-5p ; hsa-mir-103a-3p ; hsa-mir-107 ; hsa-mir-15b-5p ; hsa-mir-195-5p ; hsa-mir-369-3p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-519d-5p ; hsa-mir-4291 ; hsa-mir-5692a ; hsa-mir-6074 ; hsa-mir-6838-5p ; hsa-mir-7848-3p ; hsa-mir-3613-3p ; hsa-mir-3662 ; hsa-mir-2681-5p ; hsa-mir-3646 ; hsa-mir-379-5p ; hsa-mir-3163 ; hsa-mir-3935 ; hsa-mir-4451 ; hsa-mir-4650-3p ; hsa-mir-3529-5p ; hsa-mir-6764-3p ; hsa-mir-6824-3p ; hsa-mir-7705 ; hsa-mir-7852-3p ; hsa-mir-19a-3p ; hsa-mir-19b-3p ; hsa-mir-130a-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-518a-5p ; hsa-mir-527 ; hsa-mir-454-3p ; hsa-mir-301b-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-4671-3p ; hsa-mir-4477b ; hsa-mir-559 ; hsa-mir-548b-5p ; hsa-mir-548a-5p ; hsa-mir-548c-5p ; hsa-mir-548d-5p ; hsa-mir-548j-5p ; hsa-mir-548h-5p ; hsa-mir-548i ; hsa-mir-548w ; hsa-mir-548y ; hsa-mir-548o-5p ; hsa-mir-548ab ; hsa-mir-548ad-5p ; hsa-mir-548ae-5p ; hsa-mir-548ak ; hsa-mir-548am-5p ; hsa-mir-548ap-5p ; hsa-mir-548aq-5p ; hsa-mir-548ar-5p ; hsa-mir-548as-5p ; hsa-mir-548au-5p ; hsa-mir-548ay-5p ; hsa-mir-548bb-5p ; hsa-mir-802 ; hsa-mir-3126-3p ; hsa-mir-3128 ; hsa-mir-214-3p ; hsa-mir-761 ; hsa-mir-922 ; hsa-mir-3619-5p ; hsa-mir-187-5p ; hsa-mir-221-3p ; hsa-mir-222-3p ; hsa-mir-506-5p ; hsa-mir-2053 ; hsa-mir-548v ; hsa-mir-4666a-5p ; hsa-mir-892c-5p ; hsa-mir-186-5p ; hsa-mir-548k ; hsa-mir-548l ; hsa-mir-548av-5p ; hsa-mir-8054 ; hsa-mir-5585-3p ; hsa-mir-222-5p ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-369-5p ; hsa-mir-7856-5p ; hsa-mir-6892-5p ; hsa-mir-4668-5p ; hsa-mir-3148 ; hsa-mir-329-5p ; hsa-mir-5584-5p ; hsa-mir-4475 ; hsa-mir-642a-5p ; hsa-mir-2276-5p ; hsa-mir-6892-3p ; hsa-mir-4774-5p ; hsa-mir-4490 ; hsa-mir-1273e ; hsa-mir-137 ; hsa-mir-5588-5p ; hsa-mir-4799-3p ; hsa-mir-4720-5p ; hsa-mir-6868-5p ; hsa-mir-4470 ; hsa-mir-4680-5p ; hsa-mir-569 ; hsa-mir-16-1-3p ; hsa-mir-4714-3p ; hsa-mir-1468-3p ; hsa-mir-4719 ; hsa-mir-8063 ; hsa-mir-548p ; hsa-mir-330-3p ; hsa-mir-3145-3p ; hsa-mir-6514-3p ; hsa-mir-7977 ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-564 ; hsa-mir-6847-3p ; hsa-mir-6811-3p ; hsa-mir-214-5p ; hsa-mir-4755-3p ; hsa-mir-4673 ; hsa-mir-4645-5p ; hsa-mir-6715b-5p ; hsa-mir-4269 ; hsa-mir-3622a-5p ; hsa-mir-4753-5p ; hsa-mir-8058 ; hsa-mir-5009-5p

Nearest miRNA

hsa-mir-10392/Upstream/3711210; hsa-let-7a-2/Downstream/1482702;

Nearest TSS

Nearest CpG islands

None/Target, chr11-CpG: 30/Upstream/16454, chr11-CpG: 37/Downstream/17385

Upstream sequence

GATACAACAAGACATGTTTTGTGGAGACTAAAGAATGGAGAACTGGAGAATATTAAGCCTAAGGTGAAATGAAAGTTACTTGTCAATGTCATTAATCTTA

Downstream sequence

AGTCTGTTTTGGATAGTTAAATTGTCTGAAACTGTAAAAAAAAATTGCTTCTTTAAAGACCTATTTCACTATTTTTTTCGTGCCTCTTTAAGGTAAATGA