Basic Information
VIS ID
TVIS44023203
Fusion event
HTLV-1-USP2-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
119340624/119469913 (Hg38)
End
119340624/119469913 (Hg38)
Orient
-
Location type
ncRNA_exonic
Fragile sites / regions
FRA11B
Target gene
USP2-AS1
Nearest miRNA
hsa-mir-10392/Upstream/156901; hsa-let-7a-2/Downstream/2629844;
Nearest TSS
ENST00000527297/Upstream/44928; ENST00000532153/Downstream/138510;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/46680, chr11-CpG: 81/Downstream/114529
Upstream sequence
gttcccacctggtgggaagcactgtgcaggttcgtggggatgcagccctgcacagcccagactggactccttccccatggaactcacaacacacgggaga
Downstream sequence
ggcagaGAGATCCAAGCGCACAGAAAAACACAAGAAGATTCAGCCCTGTCATCTTGTGCAAAGTGAGTTCCACATAATTCAATTATAAAATGAGAGATTG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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