Basic Information
VIS ID
TVIS44023225
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.2
Reference genome
GRCh37/hg19
Start
16629127/16607580 (Hg38)
End
16629127/16607580 (Hg38)
Orient
-
Location type
Intergenic
Fragile sites / regions
FRA11C ; FRA11I
Nearest miRNA
hsa-mir-210/Upstream/637959; hsa-let-7a-2/Downstream/1780207;
Nearest TSS
ENST00000527297/Upstream/1589; ENST00000525106/Downstream/147;
Nearest CpG islands
chr11-CpG: 65/Target, None/Upstream, None/Downstream
Nearby gene
C11orf58(No orient, 131021)
Upstream sequence
GTCACAGTCCGGGGAGCAAGGGAACAGAACCCCCCAGCGCCGCGGCCGGCGTAGCCCGTTAACTCAAGTCTGCGGGGGTGTCCCGCCCCGGGTGGGGGCA
Downstream sequence
GCGCAGAGCGGCAGAAGTTTGCCGCCGGGGTTCCAGGAGGTGCGCGCGGAGCGGGGTGACTAGGGGCTTCACCCTGGAACAAGTGAAGGCGATGGTTAGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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