Basic Information
VIS ID
TVIS44023232
Fusion event
HTLV-1-IGSF22 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
18740100/18718553 (Hg38)
End
18740100/18718553 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
IGSF22
Nearest miRNA
hsa-mir-210/Upstream/330693; hsa-let-7a-2/Downstream/856757;
Nearest TSS
ENST00000527297/Upstream/12016; ENST00000528646/Downstream/7621;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/12373, chr11-CpG: 60/Downstream/2590
Upstream sequence
tgaaacagttaagagtagagcccaattcCAGCCTCTTTCAACCATACCAGGAGGCATCCTCTTGATGGGATGGAAGAGAGGCTATGGCTTATATACAGTG
Downstream sequence
AGAGAAGGGGGTAGAGAGGAAGAGATATTGCCAAGGTGGACCCTGGCTAGGCATCCCCCACCTTGATCCATATCATCTTGACATTGGGGTCTTTCAGTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate