Basic Information
VIS ID
TVIS44023236
Fusion event
HTLV-1-CSRP3-AS1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
19316563/19295016 (Hg38)
End
19316563/19295016 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
CSRP3-AS1
Nearest miRNA
hsa-mir-210/Upstream/907156; hsa-let-7a-2/Downstream/280294;
Nearest TSS
ENST00000527297/Upstream/53396; ENST00000528326/Downstream/4867;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/52166, chr11-CpG: 59/Downstream/50090
Nearby gene
E2F8(-53361) ;
Upstream sequence
ttaccatagggttgctttggccatttgggctcttttttggtttcaaatgaattttagatttctttctttctTTTTTTTAATTAAAAAAATACagagaggg
Downstream sequence
tctcactctgtcacccaggctggagtgctgtggcatgatcttggctcactgcaacctctgccccctggctcaagcagtcctcccacttcagccttccaag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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