Basic Information
VIS ID
TVIS44023242
Fusion event
HTLV-1-LOC107984320 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
21745482/21723936 (Hg38)
End
21745482/21723936 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC107984320
Nearest miRNA
hsa-mir-210/Upstream/1963853; hsa-let-7a-2/Downstream/1695169;
Nearest TSS
ENST00000527297/Upstream/440199; ENST00000530837/Downstream/389512;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/1053637, chr11-CpG: 88/Downstream/468690
Nearby gene
NELL1(+148253) ;
Upstream sequence
ctgcttaacaaatgtAATGTTTTGCCTCTTCAACAAGCCTGCCACCCTCCTGTGATACATAATCTTTAATTGCACATGACAACATAAAATACAAATATCT
Downstream sequence
CTCTTACATTGAGGAAATTAACACATGACTTAGAGTGGGGATGTCCTGCTGGATTTCCAGAGTAGCAATTTGTCAGGTATATTGCATGTTCACTATTTGT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate