Basic Information
VIS ID
TVIS44023259
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p12
Reference genome
GRCh37/hg19
Start
36715424/36693874 (Hg38)
End
36715424/36693874 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1343/Upstream/683670; hsa-let-7a-2/Downstream/6865782;
Nearest TSS
ENST00000527297/Upstream/95595; ENST00000532562/Downstream/1244727;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/183407, chr11-CpG: 49/Downstream/6618015
Nearby gene
C11orf74(No orient, 34583)
Upstream sequence
ATGCTTAGTCTAACATTTttggtgcaaaagtaattgtagtttttgctattaaaagtaatgccaaaacccacaataacttttgcaccaacctaaTAGGTGG
Downstream sequence
CTCGTGAGTTTTAATGTAGGGATTTAGGTACCAGAGAGCCTACTGTGTCTTTTATTCTTTAGTTATCTTACACGACCCTATTTAAATTTAGGGTTGATAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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