Basic Information
VIS ID
TVIS44023273
Fusion event
HTLV-1-HSD17B12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.2
Reference genome
End
43648153/43626603 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-874-3p ; hsa-mir-191-5p ; hsa-mir-381-3p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-4771 ; hsa-mir-1205 ; hsa-mir-1972 ; hsa-mir-4494 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-509-5p ; hsa-mir-509-3-5p ; hsa-mir-4418 ; hsa-mir-3714 ; hsa-mir-548an ; hsa-mir-633 ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-510-3p ; hsa-mir-222-5p ; hsa-mir-142-3p ; hsa-mir-494-3p ; hsa-mir-29a-5p ; hsa-mir-3129-5p ; hsa-mir-199b-3p ; hsa-mir-199a-3p ; hsa-mir-936 ; hsa-mir-205-3p ; hsa-mir-4280 ; hsa-mir-3163 ; hsa-mir-3680-3p ; hsa-mir-557 ; hsa-mir-507 ; hsa-mir-450b-5p ; hsa-mir-527 ; hsa-mir-518a-5p ; hsa-mir-548aw ; hsa-mir-1288-5p ; hsa-mir-382-3p ; hsa-mir-4284 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1307-3p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4726-3p ; hsa-mir-6764-5p ; hsa-mir-1915-3p ; hsa-mir-6840-3p ; hsa-mir-5698 ; hsa-mir-744-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-675-5p ; hsa-mir-4466 ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-103b ; hsa-mir-7705 ; hsa-mir-7703 ; hsa-mir-6720-5p ; hsa-mir-6512-3p ; hsa-mir-542-3p ; hsa-mir-5186 ; hsa-mir-4252 ; hsa-mir-4793-3p ; hsa-mir-766-3p ; hsa-mir-6849-3p ; hsa-mir-598-5p ; hsa-mir-1273g-3p ; hsa-mir-508-5p ; hsa-mir-1273a ; hsa-mir-6501-3p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-7977 ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-24-3p ; hsa-mir-383-3p ; hsa-mir-3614-5p ; hsa-mir-1227-3p ; hsa-mir-3160-3p ; hsa-mir-1247-3p ; hsa-mir-340-3p ; hsa-mir-3689d ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4684-5p ; hsa-mir-548c-3p ; hsa-mir-6134 ; hsa-mir-6499-3p ; hsa-mir-6516-5p ; hsa-mir-6771-3p ; hsa-mir-6807-5p ; hsa-mir-6827-3p ; hsa-mir-6851-5p ; hsa-mir-6880-5p ; hsa-mir-7847-3p ; hsa-mir-129-5p ; hsa-mir-2113 ; hsa-mir-371b-5p ; hsa-mir-373-5p ; hsa-mir-4474-3p ; hsa-mir-4698 ; hsa-mir-5010-3p ; hsa-mir-5692a ; hsa-mir-616-5p ; hsa-mir-7108-5p ; hsa-mir-8063
Nearest miRNA
hsa-mir-129-2/Upstream/45120; hsa-let-7a-2/Downstream/2065101;
Nearby gene
MIR129-2(+45120) ;
Upstream sequence
AAATGTTTTAGTAGCAAGAAACAGAAACTATATGGCACATTAATTTTTTTTGCATTTTTTTTAATAGATGCTAAAACAATGGTTTCAGGAAAAGGAGTAT
Downstream sequence
TTTTGTTTTATCTGAGACTTATAGTACCTTAAGTAATGTTTTCAAAGGAAAATAATAATACTTTTTACAAACTTTCCATTTCAACCCTTATGCAAATGAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate