Basic Information
VIS ID
TVIS44023278
Fusion event
HTLV-1-LOC646813 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p11.12
Reference genome
GRCh37/hg19
Start
50374953/50415782 (Hg38)
End
50374953/50415782 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
LOC646813
Nearest miRNA
hsa-mir-129-2/Upstream/2318924; hsa-let-7a-2/Downstream/6328091;
Nearest TSS
ENST00000527297/Upstream/117164; ENST00000319760/Downstream/4188216;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/117181, chr11-CpG: 94/Downstream/5456810
Upstream sequence
ccatactgggctaatattgtatttttagtagagacagggtttctccattgttgttcaggttggtctcgaactcccaacctcagatgatccacccaccttg
Downstream sequence
acctcccaaaatgctgagattacaggcatgagccactgagcccggccATTAGCACTCATTCCTAATCTCCAACAACTATTAGGCTACAACTGTTCTTAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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