VISDB Viral Integration Site DataBase

VIS ID

TVIS44023292

Fusion event

HTLV-1-PLAAT3 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr11

Cytoband

q13.1

Reference genome

Start

End

63381213/63613741 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-4662a-5p ; hsa-mir-7114-3p ; hsa-mir-1180-5p ; hsa-mir-4750-3p ; hsa-mir-186-3p ; hsa-mir-548m ; hsa-mir-5692a ; hsa-mir-548c-3p ; hsa-mir-574-5p ; hsa-mir-1303 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-6787-3p ; hsa-mir-611 ; hsa-mir-3131 ; hsa-mir-1207-3p ; hsa-mir-8083 ; hsa-mir-512-5p ; hsa-mir-6832-3p ; hsa-mir-6823-3p ; hsa-mir-6885-3p ; hsa-mir-4659b-3p ; hsa-mir-4659a-3p ; hsa-mir-6809-3p ; hsa-mir-6833-3p ; hsa-mir-4768-5p ; hsa-mir-500a-3p ; hsa-mir-4753-3p ; hsa-mir-3160-5p ; hsa-mir-6804-3p ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-3667-3p ; hsa-mir-6734-3p ; hsa-mir-6800-3p ; hsa-mir-5089-5p ; hsa-mir-3166 ; hsa-mir-6506-5p ; hsa-mir-619-5p ; hsa-mir-150-5p ; hsa-mir-4692 ; hsa-mir-4514 ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4661-5p ; hsa-mir-129-5p ; hsa-mir-8055 ; hsa-mir-744-3p ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6794-3p ; hsa-mir-4423-5p ; hsa-mir-6501-5p ; hsa-mir-4524a-3p ; hsa-mir-367-5p ; hsa-mir-1267 ; hsa-mir-1304-3p ; hsa-mir-4639-3p ; hsa-mir-5007-5p ; hsa-mir-3664-5p ; hsa-mir-4797-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-6516-5p ; hsa-mir-455-3p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-2467-3p ; hsa-mir-6086 ; hsa-mir-377-5p ; hsa-mir-1827 ; hsa-mir-6840-3p ; hsa-mir-665 ; hsa-mir-4459 ; hsa-mir-4257 ; hsa-mir-4695-5p ; hsa-mir-548s ; hsa-mir-4684-5p ; hsa-mir-3926 ; hsa-mir-3190-5p ; hsa-mir-3675-3p ; hsa-mir-1273d ; hsa-mir-147a ; hsa-mir-30a-3p ; hsa-mir-30d-3p ; hsa-mir-30e-3p ; hsa-mir-5010-3p ; hsa-mir-622 ; hsa-mir-6818-5p ; hsa-mir-6844

Nearest miRNA

hsa-mir-129-2/Upstream/820970; hsa-let-7a-2/Downstream/728108;

Nearest TSS

Nearest CpG islands

chr11-CpG: 73/Target, None/Upstream, None/Downstream

Nearest cancer related gene

PLAAT3(TSG, No orient, 0)

Upstream sequence

GTCAGCTGACATAGCCCCCAAGGCCTGTCCCGCTGTCCGGGTGTGGCTCCGGAGGGCAGCGCCAGATTTCTGCGGACAGACCTGCCCTGGCCACCTCCCT

Downstream sequence

CCTGAGGGTCCCGCCTTCCGCTGGGCGCGTTTCAGGCAGGGCGCCCCCACACCGGCCCCCGGAAGGACGCGCCGAGACAACTCCCAACAGGTGCGCGCCG