Basic Information
VIS ID
TVIS44023293
Fusion event
HTLV-1-chr11 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64653424/64885952 (Hg38)
End
64653424/64885952 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA11H
Nearest miRNA
hsa-mir-10392/Upstream/7343; hsa-let-7a-2/Downstream/5185;
Nearest TSS
ENST00000527297/Upstream/6239; ENST00000413292/Downstream/2344;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/6858, chr11-CpG: 32/Downstream/9038
Nearby gene
MIR194-2HG(No orient, 2506)
Upstream sequence
TACGGGGTTATCCCTGCATCGTAGGAACTGGGGCAATTTTTATTTACTTTTCTATGTTGTCCAAATGTATATAATGGATGTACTTGACTTGtttaattgg
Downstream sequence
ggggaaatggagagaaaaagatgagaaacactctacaaaacaactgatctagactcttcaaaaatatcaaggtcttgaaaaacaaagaaaggctgaggat
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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