Basic Information
VIS ID
TVIS44023334
Fusion event
HTLV-1-C12orf42 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.2
Reference genome
GRCh37/hg19
Start
103570556/103176778 (Hg38)
End
103570556/103176778 (Hg38)
Orient
-
Location type
Intronic
Target gene
C12orf42
Nearest miRNA
hsa-let-7i/Upstream/2986829; hsa-mir-1178/Downstream/753647;
Nearest TSS
ENST00000382841/Upstream/13867; ENST00000551174/Downstream/1623;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/210927, chr12-CpG: 29/Downstream/125534
Upstream sequence
tggcaggaccaggatttgaaggtaggctgtctggctctaggatctgtgctcttcatcttcatgctgtactACCTCAAAACAAAGTCCAATCTGGCAACCA
Downstream sequence
CATAGGAAAATCATATGGGACTCTCTCAGAACTTAGGTGCCAATAAGACACCACGACCATTTGTAGTTGAAAATTATGTCCCCGTGAGTAGTTATTATTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate