Basic Information
VIS ID
TVIS44023340
Fusion event
HTLV-1-LOC112268104 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
10886380/10733781 (Hg38)
End
10886380/10733781 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC112268104
Nearest miRNA
hsa-mir-1244-3/Upstream/1494230; hsa-let-7i/Downstream/1378171;
Nearest TSS
ENST00000382841/Upstream/10469; ENST00000541949/Downstream/16453;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/10200, chr12-CpG: 63/Downstream/437391
Nearby gene
YBX3(No orient, 10427)
Upstream sequence
TATGTGTCTAGCAGACCATGGTGAGACTGTTTGAAAGTTACTACACAATTACACATATAAGATTGTCCAGCAGAAGATAAAGAAATTAAATGAGGGTAAA
Downstream sequence
TACAATCCTGTTCTGGTGTTTAGCATTACCTGGAGAGTACTTTTTGGGGGCCTGACTATAAGACCATCATTTCAGAATGGACTGTTAAAAATTAAACTTC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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