Basic Information
VIS ID
TVIS44023352
Fusion event
HTLV-1-LOC105370003 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.21
Reference genome
GRCh37/hg19
Start
116172121/115734316 (Hg38)
End
116172121/115734316 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12C
Target gene
LOC105370003
Nearest miRNA
hsa-let-7i/Upstream/2442708; hsa-mir-1178/Downstream/414244;
Nearest TSS
ENST00000382841/Upstream/94582; ENST00000549163/Downstream/20946;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/282126, chr12-CpG: 46/Downstream/182666
Nearby gene
MED13L(-224260) ;
Upstream sequence
CCTTATTAAAATCTCCAGCAGCTGATAGCTTTGTCCCTTCCGCCCTGCAGTAAAGTTCCCATCTCTCTTTCCAAATTTCCTTTCTGTTAACATCCTACCT
Downstream sequence
TGTCTAATTTAACTCCTGTAGCCTTAGATAATGAAAAGATGTAGGTGAAAAAGGAACTCAAACTTCCTAGATATGGAAGGTGGCTCCATCAGATGGCAGG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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