Basic Information
VIS ID
TVIS44023356
Fusion event
HTLV-1-LOC105370026 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.23
Reference genome
GRCh37/hg19
Start
119653609/119215804 (Hg38)
End
119653609/119215804 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA12E ; FRA12C
Target gene
LOC105370026
Nearest miRNA
hsa-let-7i/Upstream/2787486; hsa-mir-1178/Downstream/497830;
Nearest TSS
ENST00000382841/Upstream/29004; ENST00000539847/Downstream/43213;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/61433, chr12-CpG: 19/Downstream/118744
Nearby gene
HSPB8(+21058) ;
Upstream sequence
GGAGGTCCACAAAGATTCACCTCCAACTTCCTTTGTGCTCAACTTCGGCCAAAGCCCTAACCCTCCAGCTCTACTCCAACTCTCTGGAGCACCCCTACTC
Downstream sequence
TCTCTGGGCACTGAAGGCCACCCACATTTTAAGAGGACCCTGTCCTCTTTATTAGCTTCCACATACAAGTATGCAttttttctttttgagacggaatgtc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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