VISDB Viral Integration Site DataBase

VIS ID

TVIS44023358

Fusion event

HTLV-1-ATP6V0A2 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

q24.31

Reference genome

Start

End

124229616/123745069 (Hg38)

Orient

-

Location type

Intronic

Fragile sites / regions

Target gene

miRNAs that regulate target gene

hsa-mir-6721-5p ; hsa-mir-650 ; hsa-mir-3612 ; hsa-mir-4720-3p ; hsa-mir-4804-3p ; hsa-mir-4722-5p ; hsa-mir-2467-3p ; hsa-mir-1827 ; hsa-mir-219b-3p ; hsa-mir-302a-5p ; hsa-mir-6840-3p ; hsa-mir-4459 ; hsa-mir-665 ; hsa-mir-4768-3p ; hsa-mir-4761-3p ; hsa-mir-7843-5p ; hsa-mir-6879-5p ; hsa-mir-6735-5p ; hsa-mir-4632-5p ; hsa-mir-4436b-3p ; hsa-mir-6511a-5p ; hsa-mir-1910-3p ; hsa-mir-4695-5p ; hsa-mir-302f ; hsa-mir-6771-3p ; hsa-mir-4754 ; hsa-mir-1183 ; hsa-mir-3678-3p ; hsa-mir-7977 ; hsa-mir-4726-5p ; hsa-mir-4640-5p ; hsa-mir-24-3p ; hsa-mir-4284 ; hsa-mir-4755-3p ; hsa-mir-6895-5p ; hsa-mir-3158-5p ; hsa-mir-1283 ; hsa-mir-3130-3p ; hsa-mir-3190-5p ; hsa-mir-3613-3p ; hsa-mir-3614-5p ; hsa-mir-3675-3p ; hsa-mir-377-5p ; hsa-mir-3926 ; hsa-mir-4257 ; hsa-mir-4537 ; hsa-mir-455-3p ; hsa-mir-4786-5p ; hsa-mir-548s ; hsa-mir-6086 ; hsa-mir-6499-3p ; hsa-mir-6500-3p ; hsa-mir-6516-5p ; hsa-mir-6801-5p ; hsa-mir-6849-3p ; hsa-mir-873-3p

Nearest miRNA

hsa-let-7i/Upstream/208535; hsa-mir-3612/Downstream/592112;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/32109, chr12-CpG: 85/Downstream/16908

Upstream sequence

CCTGTGAGTGCACCACGCTCTGTCGTTGTCTCTGGATGCTCTGTGGTGCCACCTAGCTTCGGGCGCCACGAGTTTCTCTAGACTGTTGAGCAGGGTTCAC

Downstream sequence

GCTGCCCTGAGCGGGAGGTGCTCATTAGCCCCTGTGCATCCCAGTCCCGGACACTGGGAGGGGAGGCCAGGAGCTGGGGGGCCCTCCGTTTGGGAAGGTG