Basic Information
VIS ID
TVIS44023361
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q24.32
Reference genome
GRCh37/hg19
Start
127063062/126578516 (Hg38)
End
127063062/126578516 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12E
Nearest miRNA
hsa-let-7i/Upstream/1662857; hsa-mir-3612/Downstream/1715576;
Nearest TSS
ENST00000382841/Upstream/133635; ENST00000544711/Downstream/111744;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/386867, chr12-CpG: 83/Downstream/147716
Nearby gene
LOC100996671(No orient, 74430)
Upstream sequence
TTCTCTTTTGGAAAAGTTACTCTTGCTGGGAAAAGTCTTTGCAAAGGTGCTTGGGTTGGGAATATCTCTGACTAATAGGCAACACTGCTTCAGAAAGGGA
Downstream sequence
GAGATGAGGGTCCATGGCAAGGTAACAGCTAGGAACCCGGCTCTCCTGGGATCAAGGGGAGTGGAGGTCACAGAGTGGTGAGAGAGGAGGATGGAGAGAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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