Basic Information
VIS ID
TVIS44023373
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.3
Reference genome
GRCh37/hg19
Start
19147884/18994950 (Hg38)
End
19147884/18994950 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1244-3/Upstream/1321556; hsa-let-7i/Downstream/5217471;
Nearest TSS
ENST00000382841/Upstream/256849; ENST00000540972/Downstream/134802;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/3083350, chr12-CpG: 131/Downstream/134441
Nearby gene
PLEKHA5(+134742) ;
Upstream sequence
TTTTAAAAGAGAAGAGAGAAACAGATTGTGAGAGTTGTTGTTATTACCTTAATACAAGGAAGAAGTAACAAGAGAGAAAGATTATGGGAGATAAAAATAT
Downstream sequence
TAATAGAGGAAGATTTCAAAATATCTGAAAGAGGGTCAAAGGTTACCTTTGGAAAGGAATAATAAAGAGAAGGATTAATTAGCCTTAAGGAAATATTAAG
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate