Basic Information
VIS ID
TVIS44023378
Fusion event
HTLV-1-LMNTD1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
25743625/25590691 (Hg38)
End
25743625/25590691 (Hg38)
Orient
+
Location type
Intronic
Target gene
LMNTD1
Nearest miRNA
hsa-mir-1244-3/Upstream/1378196; hsa-let-7i/Downstream/283329;
Nearest TSS
ENST00000382841/Upstream/37408; ENST00000538081/Downstream/40059;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/204201, chr12-CpG: 155/Downstream/367567
Nearest cancer related gene
LMNTD1(TSG, No orient, 0)
Upstream sequence
aacccttccttagccccaggctgcatagcttgtggcttaaaaacagaccccttgcctcagcttgaggagaggagagggaagagtatggaggactttgtct
Downstream sequence
ggcatcttgaacgtcagccacagcaggatagagctgtgataggcagctcagcccacaacaggatagagcaccagtaagagttgtgaggccccctttccag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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