Basic Information
VIS ID
TVIS44023382
Fusion event
HTLV-1-TMTC1 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
p11.22
Reference genome
End
29890013/29737080 (Hg38)
Orient
+
Location type
Intronic
Target gene
miRNAs that regulate target gene
hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-27b-3p ; hsa-mir-3157-5p ; hsa-mir-1238-3p ; hsa-mir-6749-3p ; hsa-mir-670-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-627-3p ; hsa-mir-5695 ; hsa-mir-4666a-3p ; hsa-mir-7849-3p ; hsa-mir-3910 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3613-3p ; hsa-mir-561-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-548p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-5088-3p ; hsa-mir-665 ; hsa-mir-4691-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4661-3p ; hsa-mir-890 ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-548aw ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1468-3p ; hsa-mir-125b-2-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6776-3p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa
Nearest miRNA
hsa-mir-1244-3/Upstream/3863001; hsa-let-7i/Downstream/12586620;
Upstream sequence
AGCCCAGGATTGCCTCTATCCCGCAACAGCTAGTTCACTGCTGCGTCAGAGAGCTTTTCAAAAATTGTATTTAAAGACTGCTTACAGATGAAATGTGACA
Downstream sequence
CGTCGCACCCGACATTTCACTTTAAGGTGAAGAATGACTTTCTGAAAAGTGCTGAGCCGGGTGCTCTGAACAGAGACATCCTATTTCTCTCCAACACGAT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
Curate