VISDB Viral Integration Site DataBase

VIS ID

TVIS44023382

Fusion event

HTLV-1-TMTC1 integration

Validated

No

Detection method

HTS

Data source

download(RID)

Sample type

Disease

HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)

Quality evaluation

Normal

Reported year

2017

PubMed ID

Virus name

HTLV-1

Reference genome

Not given

Chromosome

chr12

Cytoband

p11.22

Reference genome

Start

End

29890013/29737080 (Hg38)

Orient

+

Location type

Intronic

Target gene

miRNAs that regulate target gene

hsa-mir-193b-3p ; hsa-mir-320a ; hsa-mir-27b-3p ; hsa-mir-3157-5p ; hsa-mir-1238-3p ; hsa-mir-6749-3p ; hsa-mir-670-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-627-3p ; hsa-mir-5695 ; hsa-mir-4666a-3p ; hsa-mir-7849-3p ; hsa-mir-3910 ; hsa-mir-374b-5p ; hsa-mir-374a-5p ; hsa-mir-655-3p ; hsa-mir-374c-5p ; hsa-mir-5692c ; hsa-mir-5692b ; hsa-mir-369-3p ; hsa-mir-335-3p ; hsa-mir-1305 ; hsa-mir-607 ; hsa-mir-3613-3p ; hsa-mir-561-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-548p ; hsa-mir-887-5p ; hsa-mir-6780a-5p ; hsa-mir-6779-5p ; hsa-mir-3689c ; hsa-mir-3689b-3p ; hsa-mir-3689a-3p ; hsa-mir-30b-3p ; hsa-mir-1273h-5p ; hsa-mir-6788-5p ; hsa-mir-30c-2-3p ; hsa-mir-30c-1-3p ; hsa-mir-6778-5p ; hsa-mir-1233-5p ; hsa-mir-6799-5p ; hsa-mir-6883-5p ; hsa-mir-6785-5p ; hsa-mir-4728-5p ; hsa-mir-149-3p ; hsa-mir-7106-5p ; hsa-mir-6894-5p ; hsa-mir-7160-5p ; hsa-mir-6134 ; hsa-mir-7854-3p ; hsa-mir-6884-5p ; hsa-mir-485-5p ; hsa-mir-7162-3p ; hsa-mir-5088-3p ; hsa-mir-665 ; hsa-mir-4691-3p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-4478 ; hsa-mir-4419b ; hsa-mir-3929 ; hsa-mir-4661-3p ; hsa-mir-890 ; hsa-mir-4715-3p ; hsa-mir-3064-3p ; hsa-mir-548aw ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-1468-3p ; hsa-mir-125b-2-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-519c-3p ; hsa-mir-519b-3p ; hsa-mir-519a-3p ; hsa-mir-6776-3p ; hsa-mir-497-3p ; hsa-mir-548t-3p ; hsa-mir-548ap-3p ; hsa-mir-548aa

Nearest miRNA

hsa-mir-1244-3/Upstream/3863001; hsa-let-7i/Downstream/12586620;

Nearest TSS

Nearest CpG islands

None/Target, chr12-CpG: 104/Upstream/347175, chr12-CpG: 145/Downstream/45982

Upstream sequence

AGCCCAGGATTGCCTCTATCCCGCAACAGCTAGTTCACTGCTGCGTCAGAGAGCTTTTCAAAAATTGTATTTAAAGACTGCTTACAGATGAAATGTGACA

Downstream sequence

CGTCGCACCCGACATTTCACTTTAAGGTGAAGAATGACTTTCTGAAAAGTGCTGAGCCGGGTGCTCTGAACAGAGACATCCTATTTCTCTCCAACACGAT