Proximate region of VIS (GRCh38)VISEnhancerEnhancer/PromoterPromoterGene754620657556320275984015757040287571708675719034757281627569401075698816756893447569256975683273756859467569954175700461757018017570260875687452756882147569604175696190757027817570293075723040
Basic Information
VIS ID
TVIS44023425
Fusion event
HTLV-1-LOC105369844 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
76116820/75723040 (Hg38)
End
76116820/75723040 (Hg38)
Orient
-
Location type
Intronic
Target gene
LOC105369844
Nearest miRNA
hsa-let-7i/Upstream/6138217; hsa-mir-1178/Downstream/3696217;
Nearest TSS
ENST00000382841/Upstream/24224; ENST00000549888/Downstream/241400;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/211302, chr12-CpG: 142/Downstream/308023
Nearby gene
KRR1(-211402) ;
Upstream sequence
TAAATCTTGAATCACGGTGTATGATTTTAATCAAATCTGTAATTATTATAAGCAAATAACTTCTTTAGTTTAAAGACAGAGGTTACATGTGAAACGTATA
Downstream sequence
TATAAGCAATTCAGGAATTTAGCATTGCCAAGTAATGATATGTGGCTTAGCCCTGCTTGTTTTTCAAGAAGCATCAGCATGGTTTGTGGTATTTCCTCAC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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