Basic Information
VIS ID
TVIS44023432
Fusion event
HTLV-1-LOC107984536 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
84535690/84141911 (Hg38)
End
84535690/84141911 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA12B
Target gene
LOC107984536
Nearest miRNA
hsa-let-7i/Upstream/2983450; hsa-mir-1178/Downstream/2603157;
Nearest TSS
ENST00000382841/Upstream/480192; ENST00000642846/Downstream/12427;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/1454044, chr12-CpG: 17/Downstream/769510
Nearby gene
SLC6A15(-717577) ;
Upstream sequence
GTTGTAGCTCTGACAGGACTGATAAGTATGTTCTTTGTGATACGGTGGCCAGCCAAGAAGTGCAGTCCTTTGTACTTGCTCTCCATTTTTTGGAATCTCC
Downstream sequence
ATTCCTTGTTCCCTTCACGTCTCTTCAGTTTTGCTACCCATCTCCACAAGTGATACTATTTAAGTTTTTGCCTTAACCTCTTGTATTCTTGATAACCTAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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