Basic Information
VIS ID
TVIS44023436
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q21.32
Reference genome
GRCh37/hg19
Start
88975356/88581579 (Hg38)
End
88975356/88581579 (Hg38)
Orient
+
Location type
Intergenic
Fragile sites / regions
FRA12B
Nearest miRNA
hsa-let-7i/Upstream/1836430; hsa-mir-1178/Downstream/5980210;
Nearest TSS
ENST00000382841/Upstream/728; ENST00000612250/Downstream/20283;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/690, chr12-CpG: 248/Downstream/769812
Nearby gene
KITLG(-1106) ;
Upstream sequence
TGTTTGTATAACTGGAGAACATTCCAAAGCATTTCATTAATTTTTTAAAAGAAAATATTAGCTGAACATTAACATCAGTGATCTTTAAAAGAAAGAATAA
Downstream sequence
TGTATGAGTTTAGGAATTAGTTATTTTAATAATAGAGTAGGAGTCCAAATTTGCTTTAATTAGTTCCGGTGCGTTTGTTAAACATGAATATGCCAAACCT
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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