Basic Information
VIS ID
TVIS44023445
Fusion event
HTLV-1-chr12 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
96196876/95803098 (Hg38)
End
96196876/95803098 (Hg38)
Orient
-
Location type
Intronic
Target gene
LINC02410 ; LOC105369921
Nearest miRNA
hsa-let-7i/Upstream/493114; hsa-mir-1178/Downstream/1688811;
Nearest TSS
ENST00000382841/Upstream/1; ENST00000551316/Downstream/55595;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/11677, chr12-CpG: 18/Downstream/55144
Nearby gene
NTN4(-12340) ;
Upstream sequence
AGGTGGCATGCCTGTTATAGTTTAACAGGTAGCCTCTGGGTGAGGTATAGTAGTTCAGATAACTTTGGATGCTTTGGATGCTCTCATGTGTGGCAGTATG
Downstream sequence
CACTTGCTAAAACATTCTCCTCTCTGGGTCTGGAAGCCTAGAGTCTATATCCATATGAGGCACTGGGCAGGTATTCCAGACTTCTGAGTCATGGATGAAA
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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