Basic Information
VIS ID
TVIS44023446
Fusion event
HTLV-1-CFAP54 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr12
Cytoband
q23.1
Reference genome
GRCh37/hg19
Start
97232580/96838802 (Hg38)
End
97232580/96838802 (Hg38)
Orient
+
Location type
Intronic
Target gene
CFAP54
Nearest miRNA
hsa-let-7i/Upstream/1528818; hsa-mir-1178/Downstream/653107;
Nearest TSS
ENST00000382841/Upstream/190827; ENST00000557092/Downstream/68421;
Nearest CpG islands
None/Target, chr12-CpG: 104/Upstream/348843, chr12-CpG: 64/Downstream/68222
Upstream sequence
aagatgagatttgggtgggaacacaaagctaaccatatcaGATGGGAAAGACAGAGTCCTTGACCCAAAAAGGCTGACAGTCTAGAAGGAAGGGATGTGT
Downstream sequence
CTTTTGCTTACATACAAAGACAATGGTTTTGTGTTTAAAATGGATGATTGTTTTGCACAAagatggggagaatgaagtgggccaggtgacaagacttgcc
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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