Basic Information
VIS ID
TVIS44023456
Fusion event
HTLV-1-MYO16 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q33.3
Reference genome
GRCh37/hg19
Start
109184357/108532009 (Hg38)
End
109184357/108532009 (Hg38)
Orient
-
Location type
Intronic
Target gene
MYO16
miRNAs that regulate target gene
hsa-mir-4695-3p ; hsa-mir-602 ; hsa-mir-8485 ; hsa-mir-548b-3p ; hsa-mir-3133
Nearest miRNA
hsa-mir-1267/Upstream/1000761; hsa-mir-4502/Downstream/1808949;
Nearest TSS
ENST00000623511/Upstream/196561; ENST00000467639/Downstream/64143;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/35338, chr13-CpG: 22/Downstream/595326
Nearby gene
MYO16(+64143) ;
Upstream sequence
tcatcaaaagcagaaggcccggcctggtggctcacgcctgtaatcctagcactttgggaggccaagaagggcagatcacttgaggttaggggttcgagac
Downstream sequence
cagcctggtcaacatggtgaaaccctgtcttactgaaaatacaaaaattagccaggcgtagtggtgcacacctgtaatcccagctacttgggaggctgag
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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