Basic Information
VIS ID
TVIS44023458
Fusion event
HTLV-1-chr13 integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
110471019/109818672 (Hg38)
End
110471019/109818672 (Hg38)
Orient
+
Location type
Intergenic
Nearest miRNA
hsa-mir-1267/Upstream/2287424; hsa-mir-4502/Downstream/522286;
Nearest TSS
ENST00000623511/Upstream/13355; ENST00000411690/Downstream/167893;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/30839, chr13-CpG: 23/Downstream/50960
Nearby gene
IRS2(-32105) ;
Nearest cancer related gene
IRS2(OG, -32105) ;
Upstream sequence
CTCCGCTGGAAAAAGAAGTATCAGGTCAATAAAATCACATTTATGTCCTGCGAGGAGACCTGATGAATGAACTGGAGGGTGAGACACAAGCAGAGGTGCC
Downstream sequence
ACCAGGGCCAGATGTGGGAGAGCAGAGCATGCCAGGCTCCGGGCTCCGCTTCAGAGGAGCGGAAGTACTGCCAGGTGGCAGCTCCCATCTTGCCGCCATC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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