Basic Information
VIS ID
TVIS44023461
Fusion event
HTLV-1-SOX1-OT integration
Validated
No
Detection method
HTS
Data source
download(RID)
Sample type
Nontumor
Disease
HTLV-1 associated myelopathy/tropical spastic paraparesis (HAM/TSP)
Quality evaluation
Normal
Reported year
2017
PubMed ID
29186194
Virus Sequence
Virus name
HTLV-1
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q34
Reference genome
GRCh37/hg19
Start
112690584/112036270 (Hg38)
End
112690584/112036270 (Hg38)
Orient
+
Location type
ncRNA_intronic
Target gene
SOX1-OT
Nearest miRNA
hsa-mir-1267/Upstream/1695241; hsa-mir-4502/Downstream/1226650;
Nearest TSS
ENST00000623511/Upstream/136282; ENST00000330949/Downstream/31377;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/20295, chr13-CpG: 35/Downstream/601
Upstream sequence
GGCAGGTAGTTCTGCCTTTCCCAAGGTGGCTGCGTGGGGGTCGCACTGCCTCTCCCGCCTTAGAAACGGCCCCAGTGATGCAAACGGCTCCGAGTGCACG
Downstream sequence
AGATCTCTCTGAAATTTGTCAAATGAGAGTTGAAGCTCTGCAACTACCCATACGTAGCCCGGGGCCCTGCATTTTCCTCAGCAGCAGGGCCAGGCCCACC
Reference
Furuta, R., et al.Human T-cell leukemia virus type 1 infects multiple lineage hematopoietic cells in vivo. PLoS Pathog,2017,13(11): e1006722.
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